Selected publications

Cancer Stem Cells Sensitivity Assay (STELLA) in Patients with Advanced Lung and Colorectal Cancer: A Feasibility Study
D’Arcangelo M, Todaro M, Salvini J, Benfante A, Colorito ML, D’Incecco A, Landi L, Apuzzo T, Rossi E, Sani S, Stassi G, Cappuzzo F.
PLoS One. 2015 May 8;10(5):e0125037
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A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology
Tate CM, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, Ricci-Vitiani L, D’Alessandris QG, Morgante L, Giannetti S, Maria Larocca L, Todaro M, Benfante A, Colorito ML, Stassi G, De Maria R, Rowlinson S, Stancato L.
PLoS One. 2015 Apr 28;10(4):e0125697
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By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy
Petrelli A, Carollo R, Cargnelutti M, Iovino F, Callari M, Cimino D ,Todaro M ,Mangiapane LR, Giammona A, Cordova A, Montemurro F, Taverna D, Daidone MG, Stassi G, Giordano S.
Oncotarget. 2015 Feb 10;6(4):2315-30
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Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging
Tirinato L, Liberale C, Di Franco S, Candeloro P, Benfante A, La Rocca R, Potze L, Marotta R, Ruffilli R, Rajamanickam VP, Malerba M, De Angelis F, Falqui A, Carbone E, Todaro M,Medema JP, Stassi G, Di Fabrizio E.
Stem Cells. 2015 Jan;33(1):35-44. I.F 7.7
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Elimination of quiescent/slow-proliferating cancer stem cells by Bcl-XL inhibition in non-small cell lung cancer.
Zeuner A, Francescangeli F, Contavalli P, Zapparelli G, Apuzzo T, Eramo A, Baiocchi M, De Angelis ML, Biffoni M, Sette G, Todaro M, Stassi G, De Maria R.
Cell Death Differ. 2014 Jul 18. IF 8.849
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Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.
Ciavardelli D, Rossi C, Barcaroli D, Volpe S, Consalvo A, Zucchelli M, De Cola A, Scavo E, Carollo R, D’Agostino D, Forlì F, D’Aguanno S, Todaro M, Stassi G, Di Ilio C, De Laurenzi V, Urbani A.
Cell Death Dis. 2014 Jul 17
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CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.
Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S, Cocorullo G, Gulotta G, Dieli F, De Maria R, Stassi G.
Cell Stem Cell. 2014 Mar 6;14(3):342-56,  I.F 23.56
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p63 isoforms regulate metabolism of cancer stem cells.
D’Aguanno S, Barcaroli D, Rossi C, Zucchelli M, Ciavardelli D, Cortese C, De Cola A, Volpe S, D’Agostino D, Todaro M, Stassi G, Di Ilio C, Urbani A, De Laurenzi V.
J Proteome Res. 2014 Apr 4;13(4):2120-36. I.F. 5.06
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TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells
Bartucci M, Dattilo R, Moriconi C, Pagliuca A, Mottolese M, Federici G, Benedetto AD, Todaro M, Stassi G, Sperati F, Amabile MI, Pilozzi E, Patrizii M, Biffoni M, Maugeri-Saccà M, Piccolo S, De Maria R.
Oncogene. 2014 Feb 17 I.F 8.55
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Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4
Volonté A, Di Tomaso T, Spinelli M, Todaro M, Sanvito F, Albarello L, Bissolati M, Ghirardelli L, Orsenigo E, Ferrone S, Doglioni C, Stassi G, Dellabona P, Staudacher C, Parmiani G, Maccalli C.
J Immunol. 2014 Jan 1;192(1):523-32. I.F. 5.52
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Combining conventional chemotherapy and γδ T cell-based immunotherapy to target cancer-initiating cells.
Todaro M, Meraviglia S, Caccamo N, Stassi G, Dieli F.
Oncoimmunology. 2013 Sep 1;2(9)
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Erythropoietin activates cell survival pathways in breast cancer stem-like cells to protect them from chemotherapy. 
Todaro M, Turdo A, Bartucci M, Iovino F, Dattilo R, Biffoni M, Stassi G, Federici G, De Maria R, Zeuner A.
Cancer Res. 2013 Nov 1;73(21):6393-400 I.F 9.28
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Chemotherapy sensitizes colon cancer initiating cells to Vγ9Vδ2 T cell-mediated cytotoxicity.
Todaro M, Orlando V, Cicero G, Caccamo N, Meraviglia S, Stassi G, Dieli F.
PLoS One. 2013 Jun 6;8(6):e65145. If. 3.73
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Distribution, function and predictive value of tumor-infiltrating γδ T lymphocytes. 
Dieli F, Stassi G, Todaro M, Meraviglia S, Caccamo N, Cordova A.
Oncoimmunology. 2013 Apr 1;2(4):e23434.
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Human NK cells selective targeting of colon cancer-initiating cells: a role for natural cytotoxicity receptors and MHC class I molecules.
Tallerico R, Todaro M, Di Franco S, Maccalli C, Garofalo C, Sottile R, Palmieri C, Tirinato L, Pangigadde PN, La Rocca R, Mandelboim O, Stassi G, Di Fabrizio E, Parmiani G, Moretta A, Dieli F, Kärre K, Carbone E.
J Immunol. 2013 Mar 1;190(5):2381-90. I.F 5.52
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Characterization of Human γδ T Lymphocytes Infiltrating Primary Malignant Melanomas.
Cordova A, Toia F, La Mendola C, Orlando V, Meraviglia S, Rinaldi G, Todaro M, Cicero G, Zichichi L, Donni PL, Caccamo N, Stassi G, Dieli F, Moschella F.
PLoS One. 2012;7(11)
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Mechanisms underlying lineage commitment and plasticity of human γδ T cells.
Caccamo N, Todaro M, Sireci G, Meraviglia S, Stassi G, Dieli F.
Cell Mol Immunol. 2013 Jan;10(1):30-4
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IL-21 regulates the differentiation of a human γδ T cell subset equipped with B cell helper activity
Caccamo N, Todaro M, La Manna MP, Sireci G, Stassi G, Dieli F.
PLoS One. 2012;7(7):e41940
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Differentiation, phenotype, and function of interleukin-17-producing human V{gamma}9V{delta}2 T cells.
Caccamo N, La Mendola C, Orlando V, Meraviglia S, Todaro M, Stassi G, Sireci G, Fournié JJ, Dieli F.
Blood. 2011 Jul 7;118(1):129-38. IF 9.9
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Carboxyamidotriazole inhibits cell growth of imatinib-resistant chronic myeloid leukaemia cellsincluding T315I Bcr-Abl mutant by a redox-mediated mechanism.
Corrado C, Raimondo S, Flugy AM, Fontana S, Santoro A, Stassi G, Marfia A, Iovino F, Arlinghaus R, Kohn EC, Leo GD, Alessandro R.
Cancer Lett. 2011 Jan 28;300(2):205-14
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Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.
Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T, Maira G, Parati EA, Stassi G, Larocca LM, De Maria R.
Nature. 2010 Dec 9;468(7325):824-8. IF 36.3
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Evidences of cervical cancer stem cells derived from established cell lines.
Todaro M, Lombardo Y, Stassi G.
Cell Cycle. 2010 Apr 1;9(7). IF 5.4
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Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells.
Todaro M, Iovino F, Eterno V, Cammareri P, Gambara G, Espina V, Gulotta G, Dieli F, Giordano S, De Maria R, Stassi G.
Cancer Res. 2010 Oct 19. I.F. 7.8
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BMP4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.
Lombardo Y, Scopelliti A, Cammareri P, Todaro M, Iovino F, Ricci-Vitiani L, Gulotta G, Dieli F, De Maria R, Stassi G.
Gastroenterology. 2010 Oct 14 IF 11.7
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Optimizing Tumor-Reactive γδ T Cells for Antibody-Based Cancer Immunotherapy.
Meraviglia S, Caccamo N, Guggino G, Tolomeo M, Siragusa S, Stassi G., Dieli F.
Curr Mol Med. 2010 Nov 1;10(8):719-26. IF 4.5
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Survivin is regulated by interleukin-4 in colon cancer stem cells.
Di Stefano AB, Iovino F, Lombardo Y, Eterno V, Höger T, Dieli F, Stassi G., Todaro M.
J Cell Physiol. 2010 May 20. 225(2):555-61. I.F. 5.2
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In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients.
Meraviglia S, Eberl M, Vermijlen D, Todaro M, Buccheri S, Cicero G, La Mendola C, Guggino G, D’Asaro M, Orlando V, Scarpa F, Roberts A, Caccamo N, Stassi G., Dieli F, Hayday AC.
Clin Exp Immunol.  2010 Aug;161(2):290-7. Epub 2010 May 10. IF 3.4
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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP.
Nat Cell Biol. 2010 May;12(5):468-76
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Aurora-A is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells. 
Cammareri P., Scopelliti A., Todaro M., Eterno V., Francescangeli F., Pat Moyer M., Agrusa A., Dieli F., Zeuner A., Stassi G.
Cancer Res. 2010  Jun 1; 70(11) 4655-65 I.F. 7.8
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V{gamma}9V{delta}2 T Lymphocytes EfficientlyRecognize and Kill Zoledronate-Sensitized, Imatinib-Sensitive, andImatinib-Resistant Chronic Myelogenous Leukemia Cells.
D’Asaro M, La Mendola C, Di Liberto D, Orlando V, Todaro M, Spina M, Guggino G, Meraviglia S, Caccamo N, Messina A, Salerno A Di Raimondo F, Vigneri  P, Stassi G., Fourniè JJ, Dieli F.
J Immunol. 2010 Mar 15;184(6):3260-8. IF 5.788
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The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. 
Kemper K, Sprick MR, de Bree M, Scopelliti A, Vermeulen L, Hoek M, Zeilstra J, Pals ST, Mehmet H, Stassi G., Medema JP.
Cancer Res. 2010 Jan 15;70(2):719-29. I.F. 7.8
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Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer.
Charafe-Jauffret E, Ginestier C, Iovino F, Tarpin C, Diebel M, Esterni B, Houvenaeghel G, Extra JM, Bertucci F, Jacquemier J, Xerri L, Dontu G, Stassi G, Xiao Y, Barsky SH, Birnbaum D, Viens P, Wicha MS.
Clin Cancer Res. 2010 Jan 1;16(1):45-55
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SOCS3 sensitizes anaplastic thyroid cancer to standard chemotherapy.
Francipane M. G., Eterno V., Spina V., Bini M., Scerrino G., Buscemi G., Gulotta G., Todaro M., Dieli F., De Maria R. and Stassi G.
Cancer Res. 2009 Aug 1; 69(15):6141-8. I.F. 7.8
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Efficient killing of human colon cancer stem cells by gd T lymphocytes.
Todaro M., D’Asaro M., Caccamo N., Iovino F., Francipane M. G., Meraviglia S., Orlando V., La Mendola C., Gulotta G., Salerno A., Dieli F. and Stassi G.
Journal of Immunology. J Immunol. 2009 Jun 1;182(11):7287-96. IF 5.788
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Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.
Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P, Hur MH, Diebel ME, Monville F, Dutcher J, Brown M, Viens P, Xerri L, Bertucci F, Stassi G, Dontu G, Birnbaum D, Wicha MS.
Cancer Res. 2009 Feb 15;69(4):1302-13
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Cancer Stem Cell Analysis and Clinical Outcome in Patients with Glioblastoma Multiforme.
Pallini R., Ricci-Vitiani L., Banna G., Signore M., Lombardi D., Todaro M., Stassi G., Martini M., Maira G., La Rocca L., De Maria R.
Clin Cancer Res. 2008 Dec 15;14(24):8205-12.  I.F. 6.2
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Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.
Vermeulen L, Todaro M, de Sousa Mello F, Sprick MR, Kemper K, Perez Alea M, Richel DJ, Stassi G., Medema JP.
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13427-32. IF 9.681
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Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4.
Todaro M, Lombardo Y, Francipane MG, Alea MP,  Cammareri P, Iovino F, Di tefano SB, Di Bernardo C, Agrusa A, Condorelli G, Walczak H, Stassi G.
Cell Death Differ. 2008 Apr; 15(4): 762-72.  IF 8.849
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Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.
Todaro M, Perez Alea M, Di Stefano AB, Cammareri P, Vermeulen L, Iovino F, Tripodo C, Russo A, Gulotta G, Medema JP, and Stassi G.
Cell Stem Cell 2007; 1: 389-402. IF 25.421
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MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells. 
Siragusa M, Zerilli M, Iovino F, Francipane MG, Lombardo Y, Ricci-Vitiani L, Di Gesù G, Todaro M, De Maria R and Stassi G.
Cancer Res 2007;67(11):1–10. I.F. 7.8
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The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.
Chiappetta G, Ammirante M, Basile A, Rosati A, Festa M, Monaco M, Vuttariello E, Pasquinelli R, Arra C, Zerilli M, Todaro M, Stassi G, Pezzullo L, Gentilella A, Tosco A, Pascale M, Marzullo L, Belisario MA, Turco MC, Leone A.
J Clin Endocrinol Metab. 2007 Mar;92(3):1159-63. . I.F. 5.5
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Human Fetal Aorta Contains Vascular Progenitor Cells Capable of Inducing Vasculogenesis, Angiogenesis, and Myogenesis in Vitro and in a Murine Model of Peripheral Ischemia.
Invernici G, Emanueli C, Madeddu P, Cristini S, Gadau S, Benetti A, Ciusani E, Stassi G, Siragusa M, Nicosia R, Peschle C, Fascio U, Colombo A, Rizzuti T, Parati E, Alessandri G.
Am J Pathol. 2007 Apr 19. . I.F. 5.5
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Autocrine production of interleukin-4 and interleukin-10 is required for survival and growth of thyroid cancer cells.
Todaro M, Zerilli M, Ricci-Vitiani L, Bini M, Perez Alea M, Maria Florena A, Miceli L, Condorelli G, Bonventre S, Di Gesu G, De Maria R, Stassi G.
Cancer Res. 2006 Feb 1;66(3):1491-9 . I.F. 7.8
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Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.
Langbein S, Zerilli M, Zur Hausen A, Staiger W, Rensch-Boschert K, Lukan N, Popa J, Ternullo MP, Steidler A, Weiss C, Grobholz R, Willeke F, Alken P, Stassi G, Schubert P, Coy JF.
Br J Cancer. 2006 Feb 27;94(4):578-85. I.F. 3.8
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Altered Expression of c-IAP1, Survivin, and Smac Contributes to Chemotherapy Resistance in Thyroid Cancer Cells.
Tirro E, Consoli ML, Massimino M, Manzella L, Frasca F, Sciacca L, Vicari L, Stassi G, Messina L, Messina A, Vigneri P.
Cancer Res. 2006 Apr 15;66(8):4263-72. I.F. 7.8
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Annexin-1 Downregulation in Thyroid Cancer Correlates to the Degree of Tumor Differentiation.
Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G, Solito E, Parente L.
Cancer Biol Ther. 2006 Jun 11;5(6). I.F. 3.4
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Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction.
Eramo A, Pallini R, Lotti F, Sette G, Patti M, Bartucci M, Ricci-Vitiani L, Signore M, Stassi G, Larocca LM, Crino L, Peschle C, De Maria R.
Cancer Res. 2005 Dec 15;65(24):11469-77. I.F. 7.8
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PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells.
Stassi G, Garofalo M, Zerilli M, Ricci-Vitiani L, Zanca C, Todaro M, Aragona F, Limite G, Petrella G, Condorelli G.
Cancer Res 2005; 65: (15). August 1, 2005. I.F. 7.8
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NF-kappaB protects Behcet’s disease T cells against CD95-induced apoptosis up-regulating antiapoptotic proteins.
Todaro M, Zerilli M, Triolo G, Iovino F, Patti M, Accardo-Palumbo A, Di Gaudio F, Turco MC, Petrella A, De Maria R, Stassi G.
Arthritis Rheum. 2005 Jul;52(7):2179-91. I.F. 7.4
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Induction of annexin-1 during TRAIL-induced apoptosis in thyroid carcinoma cells.
 Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G, Solito E, Parente L.
Cell Death Differ. 2005 Oct;12(10):1358-60. I.F 8.2
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Identification and phenotypic characterization of a subpopulation of T84 human colon cancer cells, after selection on activated endothelial cells.
Alessandro R, Flugy AM, Russo D, Stassi G, De Leo A, Corrado C, Alaimo G, De Leo G.
J Cell Physiol. 2005 Apr;203(1):261-72. I.F. 5.2
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cFLIPL inhibits TNF-related apoptosis-inducing ligand-mediated NF-kappa B activation at the death inducing signalling complex (DISC) in human keratinocytes.
Wachter T, Sprick MR, Hausmann D, Kerstan A, McPherson K, Stassi G, Brocker EB, Walczak H, Leverkus M.
J Biol Chem. 2004 Dec 17;279(51):52824-34. I.F. 6.4
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Transplantation of low dose CD34+Kdr+ cells promotes vascular and muscular regeneration in ischemic limbs.
Madeddu P, Emanueli C, Pelosi E, Salis MB, Cerio AM, Bonanno G, Patti M, Stassi G, Condorelli G, Peschle C.
FASEB J. 2004 Nov;18(14):1737-9. I.F. 7.0
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Heart infarct in NOD-SCID mice: therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells.
Botta R, Gao E, Stassi G, Bonci D, Pelosi E, Zwas D, Patti M, Colonna L, Baiocchi M, Coppola S, Ma X, Condorelli G, Peschle C.
FASEB J. 2004 Sep;18(12):1392-4. I.F. 7.0
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Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs.
Lavitrano M, Smolenski RT, Musumeci A, Maccherini M, Slominska E, Di Florio E, Bracco A, Mancini A, Stassi G, Patti M, Giovannoni R, Froio A, Simeone F, Forni M, Bacci ML, D’Alise G, Cozzi E, Otterbein LE, Yacoub MH, Bach FH, Calise F.
FASEB J. 2004 Jul;18(10):1093-5. I.F. 7.0
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Identification and relevance of the CD95-binding domain in the N-terminal region of ezrin.
Lozupone F, Lugini L, Matarrese P, Luciani F, Federici C, Iessi E, Margutti P, Stassi G, Malorni W, Fais S.
J Biol Chem. 2004 Mar 5;279(10):9199-207.I.F. 6.4
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CD95 death-inducing signaling complex formation and internalizzation occur in lipid rafts of typeI and typeII cells.
Eramo A, Sargiacomo M, Ricci Vitiani L, Todaro M, Stassi G, Messina CGM, Parolini I, Peschle C, De Maria R.
Eur J Immunol. 2004 Jul;34(7):1930-40. I.F. 5.0
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Interleukin-4 protects tumor cells from CD178 and chemotherapic agents via upregulation of antiapoptotic proteins.
Conticello C, Pedini F, Zeuner A, Patti M, Zerilli M, Stassi G, Messina A, Peschle C, De Maria R.
J Immunol. 2004 May 1;172(9):5467-77.I.F. 6.5
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Islet {beta}-Cell Apoptosis Triggered in Vivo by Interleukin-1{beta} Is Not Related to the Inducible Nitric Oxide Synthase Pathway: Evidence for Mitochondrial Function Impairment and Lipoperoxidation.
Todaro M, Di Gaudio F, Lavitrano M, Stassi G, Papaccio G.
Endocrinology. 2003 Oct;144(10):4264-4271. I.F. 5.2
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Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10.
G. Stassi, M. Todaro, M. Zerilli, L. Ricci-Vitiani, D. Di Liberto, M. Patti, A. Florena, F. Di Gaudio, G. Di Gesù and R. De Maria.
Cancer Res. 2003 Oct 15;63(20):6784-90. I.F. 7.8
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Mitochondrial disruption and apoptosis in lymphocytes of an HIV infected patient affected by lactic after treatment with higly active antiretroviral theraphy.
M. Tolomeo, S. Mancuso, M. Todaro, G. Stassi, M. Catalano, S. Arista, G. Cannizzo, E. Barbusca, Abadessa V.
J Clin Pathol, Feb, 56 (2): 147-51, 2003. I.F. 2.7
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Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation.
Lavitrano M, Bacci ML, Forni M, Lazzereschi D, Di Stefano C, Fioretti D, Giancotti P, Marfe G, Pucci L, Renzi L, Wang H, Stoppacciaro A, Stassi G, Sargiacomo M, Sinibaldi P, Turchi V, Giovannoni R, Della Casa G, Seren E, Rossi G.
Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14230-5. I.F. 10.5
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 Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice.
G. Condorelli, A. Drusco, G. Stassi, A. Bellacosa, R. Roncarati, G. Iaccarino, M. A. Russo, Y. Gu, N. Dalton, C. Chung, M. V. G. Latronico, C. Napoli, J. Sadoshima, C. M. Croce, and J. Ross, Jr.
Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12333-8. I.F. 10.5
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Fluticasone induces apoptosis in peripheral T-lymphocytes: a comparison between asthmatic and normal subjects.
M. Melis, L. Siena, E. Pace, M. Giomarkaj, M. Profita, A. Pirazzoli, M. Todaro, G. Stassi, Bonsignore G, AM Vignola.
Eur Respir J. 19: 257-66 2002. I.F. 3.1.
………………………………………………………………………………………………………………………………………………………………………….
High levels of exogenous C2-Ceramide promotes morphological and biochemical evidences of necrotic features in thyroid follicular cells.
M. Todaro, M. Catalano, D. Di Liberto, M. Patti, M. Zerilli, F. Di Gaudio,G. Di Gesù, G. Vetri, G. Modica, A. Bono, M. Ciaccio, and G. Stassi.
Journal of Cellular Biochemistry, 86 (1): 162-173, 2002. I.F. 3.0.
………………………………………………………………………………………………………………………………………………………………………….
Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function.
Condorelli G, Roncarati R, Ross J Jr,Pisani A, Stassi G, Todaro M, Trocha S, Drusco A, Gu Y, Russo MA, Frati G, Jones SP, Lefer DJ, Napoli C, Croce CM.
Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9977-82. I.F. 10.45
………………………………………………………………………………………………………………………………………………………………………….
Th1 and Th2 cytokine control of thyrocyte survival in thyroid autoimmunity.
G. Stassi, A. Stoppacciaro, L. Ruco and R. De Maria.
Nature Immunol, 2: 371, 2001. I.F.27.6
………………………………………………………………………………………………………………………………………………………………………….
Response to “Thyrocytes – not innocent bystanders in autoimmune disease”
 Stassi and R. De Maria.
Nature Immunol, 2: 183, 2000 I.F. 27.6
………………………………………………………………………………………………………………………………………………………………………….
Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins.
G. Stassi, D. Di Liberto, M. Todaro, A. Zeuner, L. Ricci-Vitiani, A. Stoppacciaro, L. Ruco, F. Farina, G. Zummo, R. De Maria.
Nature Immunol, .1: 1-6, 2000 I.F. 27.6
………………………………………………………………………………………………………………………………………………………………………….
Involvement of caspase-3 and GD3 ganglioside in ceramide induced apoptosis in Farber disease.
F. Farina, F. Cappello, M. Todaro, F. Bucchieri, G. Peri, G. Zummo and G. Stassi.
Journal of Histochemistry and Cytochemistry, 48: 57-62, 2000. I.F. 2.5
………………………………………………………………………………………………………………………………………………………………………….
Adenoviral RB2/p130 gene transfer inhibits smooth muscle cell proliferation and prevents restenosis following angioplasty.
P. P. Claudio, L. Fratta, G. Stassi, C. M. Howard, F. Farina, S. Numata, C. Pacilio, A. Devis, ML. Lavitrano, M. Volpe, J. M. Wilson, B. Trimarco, A. Giordano, G. Condorelli.
Circulation Research, 85:1032-1039, 1999. I.F. 10.0
………………………………………………………………………………………………………………………………………………………………………….
Increased cardiomyocyte apoptosis and changes in pro-and anti-apoptotic genes Bax and Bcl-2 during left ventricular adaptations to chronic pressure overload in the rat.
G. Condorelli, C. Morisco, G. Stassi, A. Notte, F. Farina, G. Sgaramella, A. de Rienzo, M. Volpe, R. Roncarati, B. Trimarco and G. Lembo.
Circulation, 99:3071-3078, 1999. I.F. 12.6
………………………………………………………………………………………………………………………………………………………………………….
Defective apoptosis as potential mechanism in the tumorogenesis of myelolipoma.
Cappello F, Farina F, Di Felice V, Marcianò V, Todaro M, Balsano G, Zummo G, Stassi G.
Eur J Histochem. 1999;43(1):15-8
………………………………………………………………………………………………………………………………………………………………………….
Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis.
R. De Maria, U. Testa, L. Luchetti, A. Zeuner, G. Stassi, E. Pelosi,, R. Riccioni, N. Felli, P. Samoggia, and C. Peschle.
Blood, 93: 796-803, 1999. I.F. 9.8
………………………………………………………………………………………………………………………………………………………………………….
Fas / Fas ligand-driven T-cell apoptosis as a consequence of ineffective thyroid immunoprivilege in Hashimoto’s thyroiditis.
G. Stassi, M. Todaro, F. Bucchieri, A. Stoppacciaro, F. Farina, G. Zummo, R. Testi, and R. De Maria.
Immunol., 162:263-267, 1999. I.F. 6.486
………………………………………………………………………………………………………………………………………………………………………….
Idiopathic Dilated Cardiomyopathy: A Superantigen-Driven Autoimmune Disease.
P. Luppi, W.A. Rudert, M.M. Zanone, G. Stassi, G. Trucco, Finegold D., G. Boyle, P. Del Nido,  F. X. McGowan , M. Trucco.
Circulation, 98: 777-781, 1998. I.F. 12.563
………………………………………………………………………………………………………………………………………………………………………….
Defective expression of CD95 (FAS/APO-1) molecule suggests apoptosis impairment of T and B cells in HLA-B8, DR3-positive individuals.
G. Stassi, M. Todaro, R. De Maria, G. Candore, D. Cigna, C. Caruso, A. Galluzzo, C. Giordano.
Human Immunology. 55: 39-45, 1997. I.F. 2.7
………………………………………………………………………………………………………………………………………………………………………….
Nitric oxide primes pancreatic b-cells for Fas-mediated destruction in Insulin-dependent Diabetes Mellitus.
G. Stassi, R. De Maria, G. Trucco, W. Rudert, R. Testi, A. Galluzzo, , C. Giordano, M. Trucco.
J. Exp. Med. 186: 1193-1200, 1997. I.F. 14.6
………………………………………………………………………………………………………………………………………………………………………….
(ICA)69 is preferentially expressed in the human islets of Langerhans then exocrine pancreas.
G. Stassi, N. Schloot, M. Pietropaolo.
Diabetologia, 40: 120-124, 1997. I.F.5.6
………………………………………………………………………………………………………………………………………………………………………….
Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto’s thyroiditis.
G. Stassi, C. Giordano, R. De Maria, M. Todaro, P. Richiusa, G. Papoff, G. Ruberti, M. Bagnasco, R. Testi A. Galluzzo.
Science, 275: 960-963, 1997. I.F. 31.9
………………………………………………………………………………………………………………………………………………………………………….
Depression of CD4 T-cell subsets and alteration in cytokine profile in boutonneuse fever.
E. Cillari, S. Milano, P. D’Agostino, F. Arcoleo, G. Stassi, A. Galluzzo, P. Richiusa, C. Giordano, P. Quartararo, P. Colletti, G. Gambino, C. Mocciaro, A. Spinelli, G. Vitale, S. Mansueto.
J. Infections Disease, 174: 1051-1057, 1996. I.F. 5.0
………………………………………………………………………………………………………………………………………………………………………….
Transplantation biology. Educating effector T cells.
Trucco M, Stassi G.
Nature. 1996 Mar 28;380(6572):284-5
………………………………………………………………………………………………………………………………………………………………………….
Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human beta-cells sorted by flow-cytometry and cultured in vitro.
Stassi G, Todaro M, Richiusa P, Giordano M, Mattina A, Sbriglia MS, Lo Monte A, Buscemi G, Galluzzo A, Giordano C.
Transplant Proc. 1995 Dec;27(6):3271-5
………………………………………………………………………………………………………………………………………………………………………….
In vivo and in vitro cytokine profiles and mononuclear cell subsets in Sicilian patients with active visceral leishmaniasis.
E. Cillari, G. Viatle, F. Arcoleo, P. D’Agostino, C. Mocciaro, G. Gambino, R. Malta, G. Stassi, C. Giordano, S. Milano and S. Mansueto.
Cytokine, 7: 740-745, 1995. I.F. 2.0
………………………………………………………………………………………………………………………………………………………………………….
Defective expression of the apoptosis-inducing CD95 (Fas/APO-1) molecule on T and B cells in insulin-dependent diabetes mellitus.
C. Giordano, R. De Maria, G. Stassi, M. Todaro, P. Richiusa, M.Giordano, R. Testi and A. Galluzzo.
Diabetologia, 38: 1449-1454, 1995. I.F. 5.6
………………………………………………………………………………………………………………………………………………………………………….
T cell activation in HLA-B8, DR3 positive individuals: early antigen expression defect in vitro.
G. Candore, D. Cigna, M. Todaro, R. De Maria, G. Stassi, C. Giordano, C. Caruso.
Human Immunology, 42: 289-294, 1995. I.F. 2.7
………………………………………………………………………………………………………………………………………………………………………….
Low bcl-2 expression and increased spontaneous apoptosis in Tlymphocytes from newly diagnosed patients with insulin-dependent diabetes.
C. Giordano, G. Stassi, M. Todaro, R. De Maria, P. Richiusa, A. Scorsone, M. Giordano, A. Galluzzo.
Diabetologia, 38: 953-958, 1995. I.F. 5.6
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Defective TcR/CD3 complex signalling in human type I diabetes.
R. De Maria, M. Todaro, G. Stassi, F. Di Blasi, M. Giordano, A. Galluzzo, C. Giordano.
European Journal of Immunology, 24: 999-1002, 1994. I.F. 5.0
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Evaluation of serum levels of soluble CD4, CD8 and ß2-microglobulin in visceral human leishmaniasis.
G. Vitale, C. Mocciaro, R. Malta, G. Gambino, A. Spinelli, C. Giordano, G. Stassi, F. Arcoleo, S. Milano, E. Cillari.
Clin. Exp. Immunol., 97: 280-283, 1994. I.F. 2.4
………………………………………………………………………………………………………………………………………………………………………….
Autofluorescence-activated sorting of human single beta cells and endocrine non-beta cells after enzymatic isletdissociation.
Giordano C, Stassi G, Todaro M, Richiusa P, Giordano M, Mattina A, De Maria R, Lo Monte A, Buscemi G, Galluzzo A.
Transplant Proc. 1994 Apr;26(2):651-2
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Study of T-cell activation in Type I diabetic patients and pre-type I diabetic subjects by cytometric analysis: antigen expression defect in vitro.
C. Giordano, R. De Maria, M. Todaro, G. Stassi, A. Mattina, P. Richiusa, G. Galluzzo, F. Pantò, A. Galluzzo.
Journal of Clinical Immunology 13 (1): 68-78, 1993. I.F. 2.4
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Analysis of T-lymphocyte subsets after phytohemagglutinin stimulation in normal and Type 1 diabetic mothers and their infants.
C. Giordano, R. De Maria, A. Mattina, G. Stassi, M. Todaro, A. Pugliese, G. Galluzzo, R.M. Botta, A. Galluzzo.
American Journal of Reproductive Immunology 28: 65-70, 1992. I.F. 2.0
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Selected publications ultima modifica: 2015-10-12T12:10:22+00:00 da admin